Turner Syndrome

While Turner’s Syndrome is a genetic condition with no cure, treatment with HGH can manage the symptoms. Help your child acclimate to development by understanding Turner’s Syndrome and your treatment options.

What is Turner Syndrome?

While males have an X and a Y chromosome, females are born with two X chromosomes. Turner’s syndrome is a condition in young girls born with one of the 2 X chromosomes missing (either completely or partially).

Missing one chromosome is known as monosomy when it affects all cells within the body. If the condition results in a single chromosome in some but not all cells, it’s called mosaicism. In monosomy, the sperm cell that fertilized the egg lost its sex chromosome. In mosaicism, however, it happens early on in to fetal development. As it occurs during cell decision, it only affects a portion of the cells.

Symptoms

Turner Syndrome results in shorter height in comparison with others of the same age. Without early enough treatment, this will continue into adulthood. However, treatment with human growth hormone therapy can help.

During a prenatal ultrasound, certain signs suggest Turner syndrome, such as:

  • Kidney abnormalities
  • Delayed growth
  • Less developed nails
  • Heart abnormalities
  • Flat feet
  • Ear prominence
  • Rounded spine
  • Webbed neck

Cause

Turner syndrome is typically not hereditary, but happens due to abnormalities in chromosomes. It’s a random result of mistaken cell division during reproductive cell formation.

Diagnosis

If a doctor suspects Turner syndrome, they will run a karyotype test to establish their number of chromosomes. Through this test, they can identify if any chromosomes are abnormal. Diagnosis typically happens after birth or during puberty.

Treatment

Early diagnosis of Turner syndrome is essential for successful treatment as there’s no ultimate cure. FDA approved HGH therapy for Turner Syndrome in 1996 to help progress towards normal maturation. Endocrinologists will monitor the symptoms and recommend specific dosage for each case in HGH treatment. They may also opt for estrogen replacement therapy to help young girls develop certain physical characteristics associated with puberty.

FDA Approved Usage

HGH (Human Growth Hormone) or Somatropin has been approved to treat this condition.